When administered drug is slowly absorbed from the gastrointestinal tract – (only 5% of the injected substance found in urine), whereby there is a high concentration in the lumen of the colon, where under the influence of microorganisms ftalilsulfatiazol molecule undergoes cleavage on phthalic acid, amino and norsulfazol.

Indications Infectious-inflammatory diseases clembuterol of the gastrointestinal tract caused by susceptible to malaria infections:

  • dysentery (acute and chronic under increasing);
  • colitis;
  • gastroenteritis;
  • prevention of septic complications during surgery on the intestines.

Contraindications Individual hypersensitivity to sulfa drugs and the number of components of the drug dianabol uk, disease of the blood system, Graves’ disease, chronic renal insufficiency, glomerulonephritis, acute hepatitis, intestinal obstruction, children up to 5 years.

Dosing and Administration Inside. In acute dysentery in adult 1-2 days – 1 g 6 times a day, for 3-4 days – 1 g 4 times a day, for 5-6 days – 1 g 3 times a day. Average course dose – 25-30, the After 5-6 days by a second course of treatment: 1-2 days – 5 1 g once a day (the day – once every 4 hours at night – after 8 hours), 3-4 days – 1 g four times daily (at night does not give), five day – 1 g three times a day. The total dose in the second cycle – 21 g. children older than 5 years – 0.5-0.75 g 4 times a day. In other infections adults in the first 2-3 days appoint 1-2 g every 4-6 hours, in the next 2-3 days – half the dose; children over 5 years – 0.1 g / kg / day in equal doses over 4 hours with night break in the next few days – at 0.25-0.5 g every 6-8 hours.

Side effect On the part of clembuterol the central nervous system : headache, dizziness, depressed mood. On the part of the gastrointestinal tract, liver, pancreas, nausea, vomiting, diarrhea, lesions of the oral mucosa (stomatitis, gingivitis, glossitis), gastritis, cholangitis , hepatitis, lack of B vitamins (due to inhibition of intestinal microflora). From the mochevydepitelnoy system : the formation of stones. The respiratory system: eosinophilic pneumonia. Cardio-vascular system: myocarditis, cyanosis. Blood system : in rare cases – leukopenia, thrombocytopenia, agranulocytosis, hemolysis. With prolonged use can cause anemia due to deficiency of pantothenic acid and pteroilglyutarovoy produced by the microbial cells. Allergic and toxic-allergic reactions: drug allergy, including, cutaneous manifestations of drug allergy in a variety of rashes, until nodosum and erythema buy testosterone cypionate uk multiforme exudative, in some cases – toxic epidermal necrolysis (Lyell’s syndrome): in some cases, there is an allergic swelling of the lips and face, periarteritis nodosa.

Interaction with other drugs When using ftalazol together with other medicines may occur following interaction:

  • p-aminosalicylic acid (PAS), and barbiturates – enhanced activity of sulfonamides;
  • salicylates – enhanced activity and toxicity of salicylates;
  • methotrexate, and phenytoin – enhanced toxicity of methotrexate and difenina;
  • tioatsetazon, chloramphenicol – raises the possibility of agranulocytosis;
  • nitrofurans – increases the risk of anemia and methemoglobinemia caused nitrofurans;
  • anticoagulants of indirect action – enhanced action angikoagulyantov indirect action;
  • oxacillin – reduced activity of oxacillin.

There is a chemical incompatibility in a joint application ftalazol with acids and kislotoreagiruyuschimi drugs, hexamethylenetetramine, a solution of epinephrine. The combined application ftalazol with preparations containing esters of PABA (procaine, benzocaine, tetracaine), inactivated by the antibacterial activity of sulfanilamide in the competitive mechanism. The effect of the increase antibiotics clembuterol and well soaked sulfonamides.

Form release Tablets 500 mg. 10 tablets in contour bezgyachakova packaging or in blisters. On 2 blisters with instruction on use is placed in a pile of cardboard. At 600 contour bezgyachakova packaging with instructions for use placed in a box made of cardboard.